Etheno-2'-deoxy-β-D-adenosine

• Catalog No.: E890380
• CAS Number: 68498-25-9
• M. F.: C12H13N5O3
• M. W.: 275.26332

SYNONYMS

• IUPAC name: (2R,3R,5R)-2-(hydroxymethyl)-5-{3H-imidazo[2,1-f]purin-3-yl}oxolan-3-ol
• IUPAC Traditional name: (2R,3R,5R)-2-(hydroxymethyl)-5-{imidazo[2,1-f]purin-3-yl}oxolan-3-ol
• Synonyms: 1,N6-Ethenodeoxyadenosine; 1,N6-Etheno-dA; Ethenodeoxyadenosine; N1,N6-Etheno-2'-deoxyadenosine; 1,N6-Etheno-2'-deoxyadenosine; 3-(2-Deoxy-β-D-erythro-pentofuranosyl)-3H-imidazo[2,1-i]purine

DATABASE IDS

• CAS Number: 68498-25-9

DETAILS

Description (English)

An etheno DNA-adduct of adenosine found in atherosclerotic lesions in aorta smooth muscle cells induced via lipid peroxidation. A biomarker for genotoxicity.

REFERENCES

• Nair, J. et al.: Mut. Res. Fund. Mol. Mech. Mutagen., 621, 95 (2007)
• Meerang, M. et al.: Free Rad. Biol. Med., 44, 1863 (2007)
• Brink, A. et al.: Mut. Res. Gen. Toxicol. Env. Mutagen., 678, 123 (2007)