N2,3-Etheno-2'-deoxy Guanosine-d3

• Catalog No.: E678002
• M. F.: C12H13N5O4
• M. W.: 293.24802968

SYNONYMS

• IUPAC name: 1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl](7,8-^1^3C₂,2,7,8-^2H₃)-1H,4H,5H-imidazo[2,1-b]purin-4-one
• IUPAC Traditional name: 1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl](7,8-^1^3C₂,2,7,8-^2H₃)-5H-imidazo[2,1-b]purin-4-one
• Synonyms: 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-1H-imidazo[2,1-b]purin-4(5H)-one-d3

DETAILS

Description (English)

A labelled etheno-substituted purine nucleoside derivative with fluorescent and biochemical properties. Etheno-DNA adducts are promutagenic lesions present in normal animal and human tissues that are believed to be important in the etiol. of cancer relate

REFERENCES

• Schlatter, J., et al.: Food Chem. Toxicol., 28, 205 (1990)
• Chen, H., et al.: Chem. Res. Toxicol., 12, 1119 (1990)
• Nair, J., et al.: Mutat. Res., 424, 59 (1990)