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Ethacrynic Acid L-Cysteine Adduct_Molecular_structure_CAS_51246-37-8)
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Ethacrynic Acid L-Cysteine Adduct

Catalog No. E676010 Name Toronto Research Chemicals
CAS Number 51246-37-8 Website http://www.trc-canada.com
M. F. C16H19Cl2NO6S Telephone +1 (416) 665-9696
M. W. 424.29616 Fax +1 (416) 665-4439
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Storage Chembase ID: 168201

SYNONYMS

IUPAC name
(2R)-2-amino-3-({3-[4-(carboxymethoxy)-2,3-dichlorophenyl]-2-ethyl-3-oxopropyl}sulfanyl)propanoic acid
IUPAC Traditional name
(2R)-2-amino-3-({3-[4-(carboxymethoxy)-2,3-dichlorophenyl]-2-ethyl-3-oxopropyl}sulfanyl)propanoic acid
Synonyms
Cysteine-ethacrynic Acid Adduct
S-[2-[4-(Carboxymethoxy)-2,3-dichlorobenzoyl]butyl]-L-cysteine, Cysteine-ethacrynic Acid
Ethacrynic Acid-cysteine Complex

DATABASE IDS

CAS Number 51246-37-8

PROPERTIES

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MSDS Link Download

DETAILS

Description (English)
A metabolite of Ethacrynic Acid (E676000) that is a potent inhibitor of sodium-potassium-dichloride cotransport and bumetanide binding. Also an inhibitor of human hepatic glutathione S-transferase isozymes.

REFERENCES

  • Palfrey, H. et al.: Am. J. Physiol., 264, C1270 (1993)
  • Klaassen, C.D. et al.: J. Pharmacol. Exp. Therap., 191, 548(1993)
  • Takamatsu, Y. et al.: Toxicol. Lett., 62, 241 (1993)