Erythromycin A Oxime (Roxithromycin Impurity C)

• Catalog No.: E650010
• CAS Number: 13127-18-9
• M. F.: C37H68N2O13
• M. W.: 748.94142
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-10-(hydroxyimino)-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one
• IUPAC Traditional name: (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-10-(hydroxyimino)-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one
• Synonyms: Erythromycin Oxime; 9-Erythromycin 9-Oxime; 9-Erythromycin A Oxime; Roxithromycin Impurity C

DATABASE IDS

• CAS Number: 13127-18-9

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 159-161°C
• Solubility: Choroform
• Solubility: Dichloromethane
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

The major metabolite of Roxithromycin; also an intermediate of Azithromycin. Antibacterial agent. Roxithromycin impurity C.

REFERENCES

• Ferrero, J., et al.: Drug Metab. Dispos., 18, 441 (1990)
• Gase, C., et al.: J. Antibiot., 44, 313 (1990)
• Markham, A., et al.: Drugs, 48, 297 (1990)
• Jarukamjorn, K., et al.: J. Pharm. Pharmacol., 50, 515 (1990)