Eritadenine

• Catalog No.: E600100
• CAS Number: 23918-98-1
• M. F.: C9H11N5O4
• M. W.: 253.21474
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (2R,3R)-4-(6-amino-9H-purin-9-yl)-2,3-dihydroxybutanoic acid
• IUPAC Traditional name: (2R,3R)-4-(6-aminopurin-9-yl)-2,3-dihydroxybutanoic acid
• Synonyms: Lentysine; 4-(6-Amino-9H-purin-9-yl)-4-deoxy-D-erythronic Acid; (αR,βR)-6-Amino-α,β-dihydroxy-9H-purine-9-butanoic Acid; D-Eritadenine; Lentinacin; 4-(6-Aminopurin-9-yl)-4-deoxy-D-erythronic Acid; 4-(9-Adenyl)-D-erythro-2,3-dihydroxybutyric Acid

DATABASE IDS

• CAS Number: 23918-98-1

PROPERTIES

• Apperance: Pale Yellow Solid
• Melting Point: >270°C (dec.)
• Solubility: Sparingly soluble in DMSO and Water
• Storage Condition: Refrigerator

DETAILS

Description (English)

Hypocholesterolemic isolated from shiitake mushrooms, effecting phospholipid and linoleic acid metabolisms. Specifically, Eritadenine is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), decreasing total cholesterol levels in plasma.

REFERENCES

• Fukada, S., et al.: J. Nut., 136, 2797 (2006)
• Vilar, S., et al.: J. Med. Chem., 49, 1118 (2006)
• Yamada, T., et al.: Biochem. Pharmacol., 73, 981 (2006)
• Enman, J., et al.; J. Agric. Food Chem., 56, 2609 (2006)