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Eprosartan

Catalog No. E590100 Name Toronto Research Chemicals
CAS Number 133040-01-4 Website http://www.trc-canada.com
M. F. C23H24N2O4S Telephone +1 (416) 665-9696
M. W. 424.51266 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 754

SYNONYMS

IUPAC name
4-({2-butyl-5-[(1E)-2-carboxy-2-(thiophen-2-ylmethyl)eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid
IUPAC Traditional name
eprosartan
Synonyms
(αE)-α-[[2-Butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-2-thiophenepropanoic Acid
(E)-2-Butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic Acid
SKF 108566
Navixen
SKB 108566
Teveten

DATABASE IDS

CAS Number 133040-01-4

PROPERTIES

Certificate of Analysis Download
Apperance Light-Yellow Solid
Melting Point >246°C (dec.)
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
Eprosartan is a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists. Eprosartan is an antihypertensive.

REFERENCES

  • Edwards, R.M., et al.: J. Pharmacol. Exp. Ther., 260, 175 (1992)
  • Schambye, H.T., et al.: Mol. Pharmacol., 47, 425 (1992)
  • Tenero, D., et al.: Biopharma Drug Dispos., 19, 351 (1992)
  • Elliott, W.J., et al.: J. Hum. Hypertens., 13, 413 (1999)