6,7-Epoxy Docetaxel(Mixture of Diastereomers)

• Catalog No.: E589190
• CAS Number: 181208-36-6
• M. F.: C43H51NO14
• M. W.: 805.86334

SYNONYMS

• IUPAC name: (1S,2S,3R,4S,7R,11S,13R,16S)-4-(acetyloxy)-16-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1,13-dihydroxy-11,15,18,18-tetramethyl-12-oxo-6,9-dioxapentacyclo[12.3.1.0^3,^1^1.0^4,^7.0^8,^1^0]octadec-14-en-2-yl benzoate
• IUPAC Traditional name: (1S,2S,3R,4S,7R,11S,13R,16S)-4-(acetyloxy)-16-{[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl]oxy}-1,13-dihydroxy-11,15,18,18-tetramethyl-12-oxo-6,9-dioxapentacyclo[12.3.1.0^3,^1^1.0^4,^7.0^8,^1^0]octadec-14-en-2-yl benzoate
• Synonyms: 3a-(Acetyloxy)-4-(benzoyloxy)-1a,1b,3a,3b,4,5,6,7,10,11,11a,11b-dodecahydro-5,10-dihydroxy-8,11a,12,12-tetramethyl-11-oxo-5,9-methano-3H-cyclodec[3,4]oxireno[5,6]benz[1,2-b]oxet-7-yl Ester; β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-hydroxybenzenepropanoic Acid

DATABASE IDS

• CAS Number: 181208-36-6

DETAILS

Description (English)

A taxane derivative modified at 6 and 7 positions for use as antitumor agent.

REFERENCES

• Gaskin, F., et al.: J. Mol. Biol., 89, 737 (1974)
• Mathew, A.E., et al.: J. Med. Chem., 35, 145 (1974)