Eplerenone

• Catalog No.: E588775
• CAS Number: 107724-20-9
• M. F.: C24H30O6
• M. W.: 414.4914
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: methyl (2R,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo[8.8.0.0^1,^1^7.0^2,^7.0^1^1,^1^5]octadecan]-6'-ene-9'-carboxylate
• IUPAC Traditional name: methyl (2R,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo[8.8.0.0^1,^1^7.0^2,^7.0^1^1,^1^5]octadecan]-6'-ene-9'-carboxylate
• Synonyms: Inspra; CGP 30083; γ-Lactone 7-Methyl Ester; (7α,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxopregn-4-ene-7,21-dicarboxylic Acid; Epoxymexrenone; SC-66110

DATABASE IDS

• CAS Number: 107724-20-9

PROPERTIES

• Apperance: White Solid
• Melting Point: 241-243°C
• Solubility: Chloroform
• Solubility: Ethyl Acetate
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid rece

REFERENCES

• de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987)
• Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (1987)
• Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (1987)
• Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (1987)