7-Epi Paclitaxel

• Catalog No.: E588630
• CAS Number: 105454-04-4
• M. F.: C47H51NO14
• M. W.: 853.90614
• Storage: -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: (1S,2S,3R,4S,7R,9R,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC Traditional name: (1S,2S,3R,4S,7R,9R,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• Synonyms: 7-epi-Taxol; 7-Epitaxol; 7-Epipaclitaxel; Epitaxol

DATABASE IDS

• CAS Number: 105454-04-4

PROPERTIES

• Apperance: Off-White to Pale Yellow Solid
• Melting Point: 168-170°C (dec.)
• Solubility: Chlorform
• Solubility: Methanol
• Storage Condition: -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

The compund has been isolated from Taxus brevifolia. It is an antineoplastic that is currently being used in cancer research.

REFERENCES

• Miller, R., et al.: J. Nat. Prod., 43, 425 (1980)
• Kingston, D., et al.: Pharmacol. Therap., 52, 1 (1980)
• Wiley, R., et al.: Med. Res. Rev., 13, 327 (1980)
• Dordunoo, S., et al.: Int. J. Pharm., 133, 191 (1980)