7-Epi-10-oxo Docetaxel

• Catalog No.: E588610
• CAS Number: 162784-72-7
• M. F.: C43H51NO14
• M. W.: 805.86334

SYNONYMS

• IUPAC name: (1S,2S,3R,4S,7R,9R,10S,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1,9-dihydroxy-10,14,17,17-tetramethyl-11,12-dioxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• IUPAC Traditional name: (1S,2S,3R,4S,7R,9R,10S,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl]oxy}-1,9-dihydroxy-10,14,17,17-tetramethyl-11,12-dioxo-6-oxatetracyclo[11.3.1.0^3,^1^0.0^4,^7]heptadec-13-en-2-yl benzoate
• Synonyms: (2b,5b,7a,13a)-4-Acetoxy-13-(((2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl)oxy)-1,7-dihydroxy-9,10-dioxo-5,20-epoxytax-11-en-2-yl Benzoate

DATABASE IDS

• CAS Number: 162784-72-7

DETAILS

Description (English)

Docetaxel (D494420) injection impurity D.

REFERENCES

• Hanna, I., et al.: Cancer Res., 60, 3440 (2000)
• Bournique, B., et al.: Br. J. Clin. Pharmacol., 52, 53 (2000)
• McFadyen, M., et al.: Biochem. Pharmacol., 62, 207 (2000)
• Vasu Dev, R., et al.: J. Pharm. Biomed. Anal., 40, 614 (2000)