7-Epi Lincomycin Hydrochloride Salt

• Catalog No.: E588550
• M. F.: C18H35ClN2O6S
• M. W.: 442.9983
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (2R)-N-{2-hydroxy-1-[(3R,4R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl}-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride
• IUPAC Traditional name: (2R)-N-{2-hydroxy-1-[(3R,4R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl}-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride
• Synonyms: 7-Deoxy-7(S)-hydroxylincomycin Hydrochloride; U 20244E Hydrochloride; (7S)-Lincomycin Hydrochloride; trans-α-Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-D-galacto-octopyranoside Hydrochloride; Methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1- thio-L-threo-α-D-galacto-octopyranoside Hydrochloride; Epilincomycin Hydrochloride

PROPERTIES

• Apperance: White Solid
• Melting Point: >159°C (dec.)
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Refrigerator

DETAILS

Description (English)

An epimer of Lincomycin (L466200); a 6-amino, 6-deoxy-octopyraninose with strong antibiotic activity. A less potent bactericidal than its (7R)-epimer.

REFERENCES

• Le Goffic, F. et al.: J. Antimicrob. Chemother., 16, 12 (1985)
• Prior, C. et al.: J. Pharmacol. Exp. Therap., 255, 1170 (1985)