2'-Epi-Lamivudine

• Catalog No.: E588545
• CAS Number: 136846-20-3
• M. F.: C8H11N3O3S
• M. W.: 229.25624

SYNONYMS

• IUPAC name: 4-amino-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one
• IUPAC Traditional name: 4-amino-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
• Synonyms: (2S-trans)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; 4-Amino-1-[(2S,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; trans(-)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane

DATABASE IDS

• CAS Number: 136846-20-3

DETAILS

Description (English)

An epimer of Lamivudine (L172500); an antiviral that inhibits HIV-reverse transcriptase.

REFERENCES

• Lin, T. et al.: J. Med. Chem., 39, 1757 (1996)
• Schinazi, R.F. et al.: Antimicrob. Agents Chemother.,36, 672 (1996)