1'-Epi 3,5-Dibenzoate-2,2-difluorouridine-13C,15N2

• Catalog No.: E584502
• M. F.: C23H18F2N2O7
• M. W.: 475.37449903
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: [(2R,3R,5S)-3-(benzoyloxy)-5-[2,4-dioxo-1,2,3,4-tetrahydro(2-^1^3C,1,3-^1^5N₂)pyrimidin-1-yl]-4,4-difluorooxolan-2-yl]methyl benzoate
• IUPAC Traditional name: [(2R,3R,5S)-3-(benzoyloxy)-5-[2,4-dioxo(2-^1^3C,1,3-^1^5N₂)-3H-pyrimidin-1-yl]-4,4-difluorooxolan-2-yl]methyl benzoate
• Synonyms: 1-(3,5-Di-O-benzoyl-2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-2,4(1H,3H)-pyrimidinedione-13C,15N2

PROPERTIES

• Apperance: Amorphous White Solid
• Melting Point: 63-73°C
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Ethanol
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A labelled intermediate in the synthesis of geminal difluoro nucleoside (α-anomer).

REFERENCES

• Wiley, J., et al.: J. Clin. Invest., 69, 479 (1982)
• Gandhi, V., et al.: Cancer Res., 50, 3675 (1982)
• Abbruzzese, J., et al.: J. Clin. Oncol., 9, 491 (1982)
• Flanagan, S., et al.: J. Biol. Chem., 272, 18026 (1982)