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7-Epi 10-Desacetyl Paclitaxel_Molecular_structure_CAS_78454-17-8)
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7-Epi 10-Desacetyl Paclitaxel

Catalog No. E583500 Name Toronto Research Chemicals
CAS Number 78454-17-8 Website http://www.trc-canada.com
M. F. C45H49NO13 Telephone +1 (416) 665-9696
M. W. 811.86946 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer, Under Inert Atmosphere Chembase ID: 168036

SYNONYMS

IUPAC name
(1S,2S,3R,4S,7R,9R,10S,12R,15S)-4-(acetyloxy)-1,9,12-trihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl benzoate
IUPAC Traditional name
(1S,2S,3R,4S,7R,9R,10S,12R,15S)-4-(acetyloxy)-1,9,12-trihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl benzoate
Synonyms
10-Deacetyl-7-epi-taxol
10-Desacetyl-7-epipaclitaxel
7-Epi-10-deacetyltaxol
10-Deacetyl-7-epitaxol
Ormosin VI

DATABASE IDS

CAS Number 78454-17-8

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point 163-170°C
Solubility Chloroform
Solubility Dichloromethane
Solubility Ethanol
Solubility Ethyl acetate
Solubility Methanol
MSDS Link Download
Storage Condition -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)
Paclitaxel impurity. Paclitaxel related compound B. The compound has been isolated from Taxus yunnanensis. It has shown to have potential growth inhibitory activities against human cancer cells.

REFERENCES

  • Schiff, P., et al.: Nature, 277, 665 (1979)
  • Parness, J., et al.: J. Cell Biol., 91, 479 (1979)
  • Swindell, C., et al.: J. Med. Chem., 34, 1176 (1979)
  • Dordunoo, S., et al.: Int. J. Pharm., 133, 191 (1979)
  • Ueda, J., et al.: Planta Med. Epub (1979)