Entecavir-13C2,15N

• Catalog No.: E558902
• M. F.: C12H15N5O3
• M. W.: 280.25791857
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 2-amino-9-[(1S,3R,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-6,9-dihydro(4,6-^1^3C₂,7-^1^5N)-1H-purin-6-one
• IUPAC Traditional name: 2-amino-9-[(1S,3R,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl](4,6-^1^3C₂,7-^1^5N)-1H-purin-6-one
• Synonyms: 2-Amino-9-[4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one-13C2,15N; Baraclude-13C2,15N; SQ 34676-13C2,15N; BMS 200475-13C2,15N

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: >215°C (dec.)
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

Labelled Entecavir. An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process.

REFERENCES

• Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997)
• Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (1997)
• Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (1997)