Emtricitabine S-Oxide (Mixture of Diastereomers)

• Catalog No.: E525030
• CAS Number: 152128-77-3
• M. F.: C8H10FN3O4S
• M. W.: 263.2461032
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-3-oxo-1,3λ^4-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one
• IUPAC Traditional name: 4-amino-5-fluoro-1-[(2R,3R,5S)-2-(hydroxymethyl)-3-oxo-1,3λ^4-oxathiolan-5-yl]pyrimidin-2-one
• Synonyms: 4-Amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; [2R-(2α,5α)]-4-Amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone S-Oxide; [2R-(2α,5α)]-4-Amino-5-fluoro-1-[2-(hydroxymethyl)-3-oxido-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone

DATABASE IDS

• CAS Number: 152128-77-3

PROPERTIES

• Apperance: White Solid
• Melting Point: 212-213°C (dec.)
• Solubility: Methanol (Sparingly)
• Solubility: Water (Sparingly)
• Storage Condition: Refrigerator

DETAILS

Description (English)

A metabolite of (-)-Emtricitabine (E525000).

REFERENCES

• Schinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992)
• Shockeor, J.P., et al.: Xenobioica, 26, 189 (1992)
• Feng, J.Y., et al.: FASEB J., 13, 1511 (1992)
• Molina, J.-M., et al.: J. Infec. Dis., 182, 599 (1992)