Emtricitabine O-β-D-Glucuronide

• Catalog No.: E525025
• CAS Number: 152128-78-4
• M. F.: C14H18FN3O9S
• M. W.: 423.3708232

SYNONYMS

• IUPAC name: (2S,3S,4S,5R,6R)-6-{[(2R,5S)-5-(4-amino-5-fluoro-2-oxo-1,2-dihydropyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2S,3S,4S,5R,6R)-6-{[(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: (2R-cis)-[5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl β-D-Glucopyranosiduronic Acid

DATABASE IDS

• CAS Number: 152128-78-4

DETAILS

Description (English)

A metabolite of (-)-Emtricitabine (E525000).

REFERENCES

• Schinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992)
• Shockeor, J.P., et al.: Xenobioica, 26, 189 (1992)
• Feng, J.Y., et al.: FASEB J., 13, 1511 (1992)
• Molina, J.-M., et al.: J. Infec. Dis., 182, 599 (1992)