Emtricitabine Triphosphate Sodium Salt

• Catalog No.: E525020
• M. F.: C8H13FN3O12P3S
• M. W.: 487.1864062
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: ({[({[(2R,5S)-5-(4-amino-5-fluoro-2-oxo-1,2-dihydropyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid
• IUPAC Traditional name: ({[(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxyphosphonic acid
• Synonyms: Triphosphoric Acid P-[[(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl] Ester Sodium; Emtricitabine 5'-Triphosphate Sodium; Triphosphoric Acid (2R-cis)-P-[[5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl] Ester Sodium

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 180-184°C (dec.)
• Solubility: Water
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

A metabolite of (-)-Emtricitabine (E525000).

REFERENCES

• Barditch-Crovo, P., et al.: Antimicrob. Agents Chemother., 45, 2733 (2001)
• Ray, A., et al.: Antivir .Ther., 10, 451 (2001)
• Borroto-Esoda, K., et al.: Antivir. Ther., 11, 377 (2001)