Emtricitabine-13C,15N2

• Catalog No.: E525002
• M. F.: C8H10FN3O3S
• M. W.: 250.22617583
• Storage: Hygroscopic, Store under Inert atmosphere -20°C Freezer

SYNONYMS

• IUPAC name: 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydro(2-^1^3C,1,3-^1^5N₂)pyrimidin-2-one
• IUPAC Traditional name: 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl](2-^1^3C,1,3-^1^5N₂)pyrimidin-2-one
• Synonyms: Coviracil-13C,15N2; (-)-2'-Deoxy-5-fluoro-3'-thiacytidine-13C,15N2; BW 524W91-13C,15N2; BW 1592-13C,15N2; (-)-FTC-13C,15N2; 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone-13C,15N2; (-)-2’,3’-Dideoxy-5-fluoro-3’-thiacytidine-13C,15N2; Emtriva-13C,15N2

PROPERTIES

• Apperance: White to Off-White Solid
• Solubility: Methanol
• Solubility: Water
• Storage Condition: Hygroscopic, Store under Inert atmosphere -20°C Freezer

DETAILS

Description (English)

Labelled Emtricitabine. A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).

REFERENCES

• Schinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992)
• Shockeor, J.P., et al.: Xenobioica, 26, 189 (1992)
• Feng, J.Y., et al.: FASEB J., 13, 1511 (1992)
• Molina, J.-M., et al.: J. Infec. Dis., 182, 599 (2000)