Emtricitabine

• Catalog No.: E525000
• CAS Number: 143491-57-0
• M. F.: C8H10FN3O3S
• M. W.: 247.2467032
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one
• IUPAC Traditional name: emtricitabine
• Synonyms: BW 1592; Coviracil; (-)-2’,3’-Dideoxy-5-fluoro-3’-thiacytidine; (-)-2'-Deoxy-5-fluoro-3'-thiacytidine; Emtriva; (-)-FTC; 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone; BW 524W91

DATABASE IDS

• CAS Number: 143491-57-0

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 153-155°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).

REFERENCES

• Schinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992)
• Shockeor, J.P., et al.: Xenobioica, 26, 189 (1992)
• Feng, J.Y., et al.: FASEB J., 13, 1511 (1992)
• Molina, J.-M., et al.: J. Infec. Dis., 182, 599 (2000)