Eltrombopag-13C4

• Catalog No.: E508002
• M. F.: C25H22N4O4
• M. W.: 446.43719935

SYNONYMS

• IUPAC name: 3-(3-{2-[(4Z)-1-(3,4-dimethylphenyl)-3-(^1^3C)methyl-5-oxo-4,5-dihydro(3,4,5-^1^3C₃)-1H-pyrazol-4-ylidene]hydrazin-1-yl}-2-hydroxyphenyl)benzoic acid
• IUPAC Traditional name: 3-(3-{2-[(4Z)-1-(3,4-dimethylphenyl)-3-(^1^3C)methyl-5-oxo(3,4,5-^1^3C₃)pyrazol-4-ylidene]hydrazin-1-yl}-2-hydroxyphenyl)benzoic acid
• Synonyms: SB 497115-13C4; 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid-13C4

DETAILS

Description (English)

An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia

REFERENCES

• Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007)
• Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2007)
• Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2007)