Elacridar

• Catalog No.: E489000
• CAS Number: 143664-11-3
• M. F.: C34H33N3O5
• M. W.: 563.64292
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: N-{4-[2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]phenyl}-5-methoxy-9-oxo-9,10-dihydroacridine-4-carboxamide
• IUPAC Traditional name: N-{4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl}-5-methoxy-9-oxo-10H-acridine-4-carboxamide
• Synonyms: GG 918; N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide; GF 120918; GW 0918

DATABASE IDS

• CAS Number: 143664-11-3

PROPERTIES

• Apperance: Yellow Solid
• Melting Point: 216-218°C
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A prototypical BCRP inhibitor. Inhibits the Bcrp1-mediated transport.

REFERENCES

• Neville, K., et al.: Clin. Cancer Res., 10, 2525 (2004)
• Reardon, D., et al.: J. Clin. Oncol. 23, 9359 (2004)
• Pan, G., et al.: Drug Metab. Dispos., 35, 1165 (2004)