Enalkiren

• Catalog No.: E555450
• CAS Number: 113082-98-7
• M. F.: C35H56N6O6
• M. W.: 656.85574

SYNONYMS

• IUPAC name: 3-amino-N-[(1S)-1-{[(1S)-1-{[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-5,5-dimethylhexan-2-yl]carbamoyl}-2-(1H-imidazol-5-yl)ethyl]carbamoyl}-2-(4-methoxyphenyl)ethyl]-3-methylbutanamide
• IUPAC Traditional name: 3-amino-N-[(1S)-1-{[(1S)-1-{[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-5,5-dimethylhexan-2-yl]carbamoyl}-2-(3H-imidazol-4-yl)ethyl]carbamoyl}-2-(4-methoxyphenyl)ethyl]-3-methylbutanamide
• Synonyms: N-(3-Amino-3-methyl-1-oxobutyl)-O-methyl-L-tyrosyl-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-histidinamide; [1S-(1R*,2S*,3R*)]-N-(3-Amino-3-methyl-1-oxobutyl)-O-methyl-L-tyrosyl-N-[1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-histidinamide

DATABASE IDS

• CAS Number: 113082-98-7

DETAILS

Description (English)

An active renin inhibitor for treating vascular diseases.

REFERENCES

• Yap, C., et al.: Toxicol. Sci., 79, 170 (2004)
• Yap, C., et al.: J. Pharm. Sci., 94, 153 (2004)
• Huang, N., et al.: Med. Chem., 49, 6789 (2004)