1α,24-Dihydroxy Vitamin D2

• Catalog No.: D455105
• CAS Number: 124043-51-2
• M. F.: C28H44O3
• M. W.: 428.64716

SYNONYMS

• IUPAC name: (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E)-5-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol
• IUPAC Traditional name: (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E)-5-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-hexahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol
• Synonyms: 1α,24-Dihydroxyvitamin D2; (1R,3S,4Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E)-4-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol; 1,24-Dihydroxyvitamin D2; (1α,3β,5Z,7E,22E,24ξ)-9,10-Secoergosta-5,7,10(19),22-tetraene-1,3,24-triol

DATABASE IDS

• CAS Number: 124043-51-2

DETAILS

Description (English)

1α,24-Dihydroxyvitamin D2 is a naturally occurring metabolite of vitamin D2 (V676040) with low calcemic activity and potent antiproliferative activity. 1α,24-Dihydroxyvitamin D2 is also a metabolite of 1α-Hydroxyvitamin D2 (H995800), a prodrug in developm

REFERENCES

• Zinser, G.M. et al.: Anticancer Res., 25, 235 (2005)
• Mawer, E.B. et al.: J. Clin. Endocrinol. Metab., 83, 2156 (2005)
• Knutson, J.C. et al.: Biochem. Pharmacol., 53, 829 (2005)