2',3'-Dihydro-7'-methyl-5'-oxo-spiro[1,3-dioxolane-2,1'(5'H)-indolizine]-6'-carbonitrile_Molecular_structure_CAS_58610-64-3)

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2',3'-Dihydro-7'-methyl-5'-oxo-spiro[1,3-dioxolane-2,1'(5'H)-indolizine]-6'-carbonitrile
Catalog No.	D453360	Name	Toronto Research Chemicals
CAS Number	58610-64-3	Website	http://www.trc-canada.com
M. F.	C12H12N2O3	Telephone	+1 (416) 665-9696
M. W.	232.23528	Fax	+1 (416) 665-4439
Purity		Email	info@trc-canada.com
Storage		Chembase ID: 167840

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SYNONYMS

IUPAC name

7'-methyl-5'-oxo-3',5'-dihydro-2'H-spiro[1,3-dioxolane-2,1'-indolizine]-6'-carbonitrile

IUPAC Traditional name

7'-methyl-5'-oxo-2',3'-dihydrospiro[1,3-dioxolane-2,1'-indolizine]-6'-carbonitrile

DATABASE IDS

CAS Number

58610-64-3

PROPERTIES

Certificate of Analysis	Download
Apperance	Grey Solid
Solubility	Dimethyl Sulfoxide
MSDS Link	Download

DETAILS

Description (English)

Used in the preparation of Camptothecin derivatives, for their therapeutic use as antitumor agents.

REFERENCES

Wani, M.C., et al.: J. Med. Chem., 29, 2358 (1986)
Miller, K.D., et al.: Invest. New Drugs, 22, 69 (1986)
Punt, C.J.A., et al.: Eur. J. Cancer, 40, 1332 (1986)
Wang, J.-Q., et al.: Bioorg. Med. Chem., 13, 549 (2005)