3',5'-Dihydrodiol Simvastatin Acid Sodium Salt

• Catalog No.: D452695
• M. F.: C25H41NaO8
• M. W.: 492.57801

SYNONYMS

• IUPAC name: sodium (3R,5R)-7-[(1S,2R,3S,5S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-3,5-dihydroxy-2,6-dimethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• IUPAC Traditional name: sodium (3R,5R)-7-[(1S,2R,3S,5S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-3,5-dihydroxy-2,6-dimethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• Synonyms: (βR,δR,1S,2R,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,3,5,6,7,8,8a-octahydro-β,δ,3,5-tetrahydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Sodium Salt

DETAILS

Description (English)

A metabolite of Simvastatin (S485000).

REFERENCES

• Pietro, D., et al.: Cardiovasc. Drug Rev., 8, 220 (1990)
• Prueksaritanont, T., et al.: Drug Metab. Dispos., 29, 1251 (1990)