3',5'-Dihydrodiol Simvastatin(Mixture of Diastereomers)

• Catalog No.: D452690
• CAS Number: 159143-77-8
• M. F.: C25H40O7
• M. W.: 452.5809
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1S,3R,7R,8S,8aR)-4,6-dihydroxy-8-{2-[(4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,6,7,8,8a-octahydronaphthalen-1-yl 2,2-dimethylbutanoate
• IUPAC Traditional name: (1S,3R,7R,8S,8aR)-4,6-dihydroxy-8-{2-[(4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,6,7,8,8a-octahydronaphthalen-1-yl 2,2-dimethylbutanoate
• Synonyms: [1S-[1α,3α,4β,6α,7β,8β(2S*,4S*),8aβ]]-Butanoic Acid 2,2-Dimethyl-1,2,3,4,6,7,8,8a-octahydro-4,6-dihydroxy-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester

DATABASE IDS

• CAS Number: 159143-77-8

PROPERTIES

• Apperance: White Solid
• Melting Point: 65-67°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A metabolite of Simvastatin (S485000).

REFERENCES

• Vyas, K.P., et al.: Drug Metab. Sispos., 18, 203 (1990)
• Nakamura, T., et al.: Xenobiotica, 21, 277 (1990)
• Cheng, H., et al.: Drug Metab. Dispos., 22, 139 (1990)