(4aS,6R,7S,7aR)-6-[4-[[(1S)-2,3-Dihydro-1H-inden-1-yl]amino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]hexahydro-2-(4-methoxyphenyl)-cyclopenta-1,3-dioxin-7-ol

• Catalog No.: D449890
• CAS Number: 905580-87-2
• M. F.: C29H30N4O4
• M. W.: 498.5729

SYNONYMS

• IUPAC name: (4aR,6S,7R,7aS)-6-(4-{[(1S)-2,3-dihydro-1H-inden-1-yl]amino}-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(4-methoxyphenyl)-hexahydro-2H-cyclopenta[d][1,3]dioxin-7-ol
• IUPAC Traditional name: (4aR,6S,7R,7aS)-6-{4-[(1S)-2,3-dihydro-1H-inden-1-ylamino]pyrrolo[2,3-d]pyrimidin-7-yl}-2-(4-methoxyphenyl)-hexahydro-2H-cyclopenta[d][1,3]dioxin-7-ol

DATABASE IDS

• CAS Number: 905580-87-2

PROPERTIES

• Apperance: Off-white Foam
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Solubility: Methanol

DETAILS

Description (English)

Used in the preparation of nucleoside derivatives as antitumor agents, E1 activating enzymes and MLN4924, an inhibitor of NEDD8-activating enzyme.

REFERENCES

• Soucy, T. et al.; Nature 458, 732 (2009)