trans (2,3)-Dihydro Tetrabenazine

• Catalog No.: D449655
• CAS Number: 171598-74-6
• M. F.: C19H29NO3
• M. W.: 319.43846
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (2S,3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol
• IUPAC Traditional name: (2S,3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol
• Synonyms: (2α,3β,11bβ)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol; (2R,3R,11bR)-rel-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol

DATABASE IDS

• CAS Number: 171598-74-6

PROPERTIES

• Apperance: white Solid
• Melting Point: 167-170°C
• Solubility: Chloroform
• Storage Condition: Refrigerator

DETAILS

Description (English)

A metabolite of Tetrabenazine in vivo. The trans izomer of Dihydrotetrabenazine is used for the treatment of hyperkinetic movement disorders.

REFERENCES

• Kilbourn, M., et al.: Eur. J. Pharmacol., 278, 249 (1995)
• Perera, R., et al.: J. Med. Chem., 46, 2599 (1995)
• Mager, D., et al.: J. Pharm. Sci., 94, 2475 (1995)
• Zheng, G., et al.: Bioorg. Med. Chem., 16, 5018 (1995)