10,11-Dihydro-10-hydroxy Carbamazepine O-β-D-Glucuronide Sodium Salt(Mixture of Diastereomers)

• Catalog No.: D449133
• M. F.: C21H21N2NaO8
• M. W.: 452.38981
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: sodium (2S,3S,4S,5R,6R)-6-({2-carbamoyl-2-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-9-yl}oxy)-3,4,5-trihydroxyoxane-2-carboxylate
• IUPAC Traditional name: sodium (2S,3S,4S,5R,6R)-6-({2-carbamoyl-2-azatricyclo[9.4.0.0^3,^8]pentadeca-1(11),3(8),4,6,12,14-hexaen-9-yl}oxy)-3,4,5-trihydroxyoxane-2-carboxylate
• Synonyms: 5-(Aminocarbonyl)-10,11-dihydro-5H-dibenz[b,f]azepin-10-yl β-D-Glucopyranosiduronic Acid Sodium Salt

PROPERTIES

• Apperance: Off-White Solid
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

DETAILS

Description (English)

10,11-Dihydro-10-hydroxy Carbamazepine O-β-D-Glucuronide is a metabolite of Carbamazepine (C175840).

REFERENCES

• Burkhart, C., et al.: Clin. Exp. Allergy, 32, 1635 (2002)
• Pearce, R., et al.: Drug Metab. Dispos., 30, 1170 (2002)
• Naisbitt, D., et al.: Mol. Pharmacol., 63, 732 (2002)
• Farrell, J., et al.: Br. J. Clin. Pharmacol., 57, 690(2002)