Dihydro Ergotamine-13C,d3 Mesylate

• Catalog No.: D449082
• M. F.: C34H41N5O8S
• M. W.: 680.77569484

SYNONYMS

• IUPAC name: (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^2,^6]dodecan-4-yl]-6-(^1^3C,^2H₃)methyl-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraene-4-carboxamide; methanesulfonic acid
• IUPAC Traditional name: (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^2,^6]dodecan-4-yl]-6-(^1^3C,^2H₃)methyl-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraene-4-carboxamide; methanesulfonic acid
• Synonyms: Morena-13C,d3; Tonopres-13C,d3; Verladyn-13C,d3; Ergont-13C,d3; Ikaran-13C,d3; Dirgotarl-13C,d3; 5'α,10α)-9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione-13C,d3 Methanesulfonate; 9,10-Dihydroergotamine-13C,d3 Monomethanesulfonate; (+)-Dihydroergotamine-13C,d3 Mesylate; Dihytamine-13C,d3; Endophleban-13C,d3; Ergomimet-13C,d3; Ergotonin-13C,d3; Migranal-13C,d3

DETAILS

Description (English)

A labelled α-androgenic blocker with selective venoconstrictor properties. Also binds to serotonin 5HT1-receptors. Antimigraine.

REFERENCES

• de Marees, et al.: Eur. J. Clin. Pharmacol., 30, 685 (1986)
• McCarthy, B.G., et al.: Headache, 29, 420 (1986)
• Ziegler, D., et al.: Neurology, 44, 447 (1986)