Dihydro Ergotamine Mesylate

• Catalog No.: D449080
• CAS Number: 6190-39-2
• M. F.: C34H41N5O8S
• M. W.: 679.78304

SYNONYMS

• IUPAC name: (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^2,^6]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraene-4-carboxamide; methanesulfonic acid
• IUPAC Traditional name: (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^2,^6]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraene-4-carboxamide; methanesulfonic acid
• Synonyms: Dihytamine; Morena; Ergotonin; 9,10-Dihydroergotamine Monomethanesulfonate (Salt); Ikaran; Ergomimet; (5'α,10α)-9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotaman-3',6',18-trione Methanesulfonate; (+)-Dihydroergotamine Mesylate; Dirgotarl; Endophleban; Ergont; Migranal; Orstanorm; Tonopres; Verladyn; Seglor

DATABASE IDS

• CAS Number: 6190-39-2

DETAILS

Description (English)

α-Androgenic blocker with selective venoconstrictor properties. Also binds to serotonin 5HT1-receptors. Antimigraine.

REFERENCES

• de Marees, et al.: Eur. J. Clin. Pharmacol., 30, 685 (1986)
• McCarthy, B.G., et al.: Headache, 29, 420 (1986)
• Ziegler, D., et al.: Neurology, 44, 447 (1986)