Dihydro Artemisinin-13C,d4

• Catalog No.: D448363
• M. F.: C15H24O5
• M. W.: 285.34071484

SYNONYMS

• IUPAC name: (1R,4S,5R,8S,9R,10S,12R,13R)-9-(^1^3C,^2H₃)methyl-1,5-dimethyl(10-^2H)-11,14,15,16-tetraoxatetracyclo[10.3.1.0^4,^1^3.0^8,^1^3]hexadecan-10-ol
• IUPAC Traditional name: (1R,4S,5R,8S,9R,10S,12R,13R)-9-(^1^3C,^2H₃)methyl-1,5-dimethyl(10-^2H)-11,14,15,16-tetraoxatetracyclo[10.3.1.0^4,^1^3.0^8,^1^3]hexadecan-10-ol
• Synonyms: DHQHS 2-13C,d4; Cotexin-13C,d4; β-Dihydroartemisinin-13C,d4; Dihydroartemisinine-13C,d4; Dihydroqinghaosu-13C,d4; Alaxin-13C,d4; Cotecxin-13C,d4; (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol-13C,d4

DETAILS

Description (English)

The labelled analogue of the main metabolite of Artemisinin, Arteether, Artemether, Artesunate. An active antimalarial metabolite.

REFERENCES

• de Vries, P., et al.: Drugs, 52, 818 (1996)
• Kamolrat, S., et al.: Antimicrob. Agents Chemother., 47, 3795 (1996)
• Mithwani, S., et al.: Br. J. Clin. Pharmacol., 57, 146 (1996)