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Dihydro Artemisinin

Catalog No. D448360 Name Toronto Research Chemicals
CAS Number 71939-50-9 Website http://www.trc-canada.com
M. F. C15H24O5 Telephone +1 (416) 665-9696
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Storage -20°C Freezer Chembase ID: 167513

SYNONYMS

IUPAC name
(1S,4S,5R,8S,9R,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-ol
IUPAC Traditional name
(1S,4S,5R,8S,9R,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-ol
Synonyms
Dihydroartemisinine
Cotecxin
Alaxin
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl- 3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-ol
β-Dihydroartemisinin
Cotexin
DHQHS 2
Dihydroqinghaosu

DATABASE IDS

CAS Number 71939-50-9

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 144-149°C
Solubility Chloroform
Solubility Dichloromethane
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
The main metabolite of Artemisinin, Arteether, Artemether, Artesunate. An active antimalarial metabolite.

REFERENCES

  • de Vries, P., et al.: Drugs, 52, 818 (1996)
  • Kamolrat, S., et al.: Antimicrob. Agents Chemother., 47, 3795 (1996)
  • Mithwani, S., et al.: Br. J. Clin. Pharmacol., 57, 146 (1996)