2',2'-Difluoro-2'-deoxyuridine-13C,15N2

• Catalog No.: D445742
• M. F.: C9H10F2N2O5
• M. W.: 267.16237903
• Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

SYNONYMS

• IUPAC name: 1-[(2R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydro(2-^1^3C,1,3-^1^5N₂)pyrimidine-2,4-dione
• IUPAC Traditional name: 1-[(2R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl](2-^1^3C,1,3-^1^5N₂)-3H-pyrimidine-2,4-dione
• Synonyms: 2’-Deoxy-2’,2’-difluorouridine-13C,15N2; 2',2'-Difluorodeoxyuridine-13C,15N2

PROPERTIES

• Storage Condition: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Apperance: Off-White Solid
• Melting Point: 132-139°C
• Solubility: Methanol
• Solubility: Water

DETAILS

Description (English)

An isotopically Labelled metabolite of Gemcitabine.

REFERENCES

• Wiley, J., et al.: J. Clin. Invest., 69, 479 (1982)
• Gandhi, V., et al.: Cancer Res., 50, 3675 (1982)
• Abbruzzese, J., et al.: J. Clin. Oncol., 9, 491 (1982)
• Flanagan, S., et al.: J. Biol. Chem., 272, 18026 (1982)