2',2'-Difluoro-2'-deoxyuridine

• Catalog No.: D445740
• CAS Number: 114248-23-6
• M. F.: C9H10F2N2O5
• M. W.: 264.1829064
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: 1-[(2R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
• IUPAC Traditional name: 1-[(2R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-pyrimidine-2,4-dione
• Synonyms: 2',2'-Difluorodeoxyuridine; 2’-Deoxy-2’,2’-difluorouridine

DATABASE IDS

• CAS Number: 114248-23-6

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 147-149°C
• Solubility: Methanol
• Solubility: Water
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A metabolite of Gemcitabine (G305000) in human plasma.

REFERENCES

• Wiley, J., et al.: J. Clin. Invest., 69, 479 (1982)
• Gandhi, V., et al.: Cancer Res., 50, 3675 (1982)
• Abbruzzese, J., et al.: J. Clin. Oncol., 9, 491 (1982)
• Flanagan, S., et al.: J. Biol. Chem., 272, 18026 (1982)