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2',2'-Difluoro-2'-deoxyuridine_Molecular_structure_CAS_114248-23-6)
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2',2'-Difluoro-2'-deoxyuridine

Catalog No. D445740 Name Toronto Research Chemicals
CAS Number 114248-23-6 Website http://www.trc-canada.com
M. F. C9H10F2N2O5 Telephone +1 (416) 665-9696
M. W. 264.1829064 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage -20°C Freezer Chembase ID: 167404

SYNONYMS

IUPAC name
1-[(2R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
IUPAC Traditional name
1-[(2R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-pyrimidine-2,4-dione
Synonyms
2',2'-Difluorodeoxyuridine
2’-Deoxy-2’,2’-difluorouridine

DATABASE IDS

CAS Number 114248-23-6

PROPERTIES

Certificate of Analysis Download
Apperance White to Off-White Solid
Melting Point 147-149°C
Solubility Methanol
Solubility Water
MSDS Link Download
Storage Condition -20°C Freezer

DETAILS

Description (English)
A metabolite of Gemcitabine (G305000) in human plasma.

REFERENCES

  • Wiley, J., et al.: J. Clin. Invest., 69, 479 (1982)
  • Gandhi, V., et al.: Cancer Res., 50, 3675 (1982)
  • Abbruzzese, J., et al.: J. Clin. Oncol., 9, 491 (1982)
  • Flanagan, S., et al.: J. Biol. Chem., 272, 18026 (1982)