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(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate_Molecular_structure_CAS_376608-71-8)
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(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate

Catalog No. D446035 Name Toronto Research Chemicals
CAS Number 376608-71-8 Website http://www.trc-canada.com
M. F. C17H17F2NO3 Telephone +1 (416) 665-9696
M. W. 321.3185864 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 167375

SYNONYMS

IUPAC name
(1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine; (2R)-2-hydroxy-2-phenylacetic acid
IUPAC Traditional name
(-)-mandelic acid; (1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine
Synonyms
(αR)-α-Hydroxybenzeneacetic Acid compd. with (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine

DATABASE IDS

CAS Number 376608-71-8

PROPERTIES

Certificate of Analysis Download
Apperance Off-White Solid
Melting Point 158-162°C
Solubility DMSO
Solubility Methanol
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate in the preparation of orally active reversible P2Y12 receptor antagonists for the prevention of thrombosis.

REFERENCES

  • Springthorpe, B. et al.: Bioorg. Med. Chem. Lett., 17, 6013 (2007)