1,4-Dideoxy-1,4-imino-D-mannitol, Hydrochloride

• Catalog No.: D439980
• CAS Number: 114976-76-0
• M. F.: C6H14ClNO4
• M. W.: 199.63266

SYNONYMS

• IUPAC name: (2R,3S,4R)-2-[(1S)-1,2-dihydroxyethyl]pyrrolidine-3,4-diol hydrochloride
• IUPAC Traditional name: (2R,3S,4R)-2-[(1S)-1,2-dihydroxyethyl]pyrrolidine-3,4-diol hydrochloride
• Synonyms: (2R,3S,4R)-2-[(1S)-1,2-Dihydroxyethyl]-3,4-pyrrolidinediol Hydrochloride

DATABASE IDS

• CAS Number: 114976-76-0

PROPERTIES

• Apperance: White Needles
• Melting Point: 147-148°C
• Solubility: Water

DETAILS

Description (English)

A competitive glycosidase inhibitor. It is also a glycoprotein mannosidase inhibitor - inhibiting jack bean, and to a lesser extent lysosomal alpha-mannosidase. It is an azofuranose analog of mannose, and is structurally related to swainsonine.

REFERENCES

• Bashyal, B.P., et al.: Tetrahedron, 43, 3083-3093 (1987)