Diclofenamide

• Catalog No.: D436530
• CAS Number: 120-97-8
• M. F.: C6H6Cl2N2O4S2
• M. W.: 305.15884
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 4,5-dichlorobenzene-1,3-disulfonamide
• IUPAC Traditional name: dichlorphenamide
• Synonyms: 1,3-Disulfamyl-4,5-dichlorobenzene; Oratrol; Antidrasi; 3,4-Dichloro-5-sulfamylbenzenesulfonamide; Dichlorophenamide; Glaucol; Dichlofenamide; 1,3-Disulfamoyl-4,5-dichlorobenzene; 4,5-Dichloro-1,3-disulfamoylbenzene; 4,5-Dichloro-m-benzenedisulfonamide; CB 8000; Daramide; Daranide; Dichlorphenamide; Diclofenamid

DATABASE IDS

• CAS Number: 120-97-8

PROPERTIES

• Apperance: Off-White Solid
• Melting Point: 237-240°C
• Solubility: Chloroform
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

Diclofenamide is a potent carbonic anhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-associated isoenzymes IX and XII. Diclofenamide has been shown to b

REFERENCES

• Brzozowski, Z. et al.: Eur. J. Med. Chem., 46, 3656 (2010)
• Tawil, R. et al.: Ann. Neurol., 47, 46 (2010)
• Casey, J. et al.: J. Med. Chem., 47, 2337 (2010)