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cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol_Molecular_structure_CAS_61397-58-8)
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cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol

Catalog No. D435930 Name Toronto Research Chemicals
CAS Number 61397-58-8 Website http://www.trc-canada.com
M. F. C14H14Cl2N2O3 Telephone +1 (416) 665-9696
M. W. 329.17856 Fax +1 (416) 665-4439
Purity Email info@trc-canada.com
Storage Refrigerator Chembase ID: 167162

SYNONYMS

IUPAC name
[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methanol
IUPAC Traditional name
[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methanol
Synonyms
(2R,4S)-rel-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol

DATABASE IDS

CAS Number 61397-58-8

PROPERTIES

Certificate of Analysis Download
Apperance White Solid
Melting Point 130-132°C
Solubility Chloroform
Solubility DMSO
MSDS Link Download
Storage Condition Refrigerator

DETAILS

Description (English)
cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol is a Ketoconazole (K186000) fragment that may have modulatory activity on the large conductance calcium-activated potassium channel (BKCa).

REFERENCES

  • Power, E.C. et al.: Bioorg. Med. Chem., 16, 887 (2006)
  • Heeres, J. et al.: J. Med. Chem., 22, 1003 (2006)