5,6-Dichloropurine-1-β-D-ribofuanosyl-H-benzimidazole

• Catalog No.: D435820
• CAS Number: 53-85-0
• M. F.: C12H12Cl2N2O4
• M. W.: 319.14068
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (2R,3S,5R)-2-(5,6-dichloro-1H-1,3-benzodiazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol
• IUPAC Traditional name: (2R,3S,5R)-2-(5,6-dichloro-1,3-benzodiazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol
• Synonyms: NSC 401575; DRB; 1-β-D-Ribofuranosyl-5,6-dichlorobenzimidazole; 5,6-Dichlorobenzimidazole 1-β-D-Ribofuranoside; 5,6-Dichloro-1-(β-D-ribofuranosyl)benzimidazole

DATABASE IDS

• CAS Number: 53-85-0

PROPERTIES

• Apperance: Off-White to Light Beige Solid
• Melting Point: 213-216°C
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

An inhibitor of RNA synthesis (causes premature termination of transcription).

REFERENCES

• Braedlye, J. and Sporns, O.: Brain Res., 815, 140 (1999)
• Ljungman, M., et al.: Oncogene, 18, 583 (1999)
• Roele, R.H., et al.: Oncogene, 18, 5765 (1999)