3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxy-8-[(3-(methyl-d3)-8-methyl-3H-imidazo[4,5-f]quinoxalin-2-yl)amino]guanosine

• Catalog No.: D429412
• M. F.: C33H50N10O4Si2
• M. W.: 706.9857
• Storage: Refrigerator

SYNONYMS

• IUPAC name: 2-amino-9-[(2R,4S,5R)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-2-yl]-8-{[3-(^2H₃)methyl-8-methyl-3H-imidazo[4,5-f]quinoxalin-2-yl]amino}-6,9-dihydro-1H-purin-6-one
• IUPAC Traditional name: 2-amino-9-[(2R,4S,5R)-4-[(tert-butyldimethylsilyl)oxy]-5-{[(tert-butyldimethylsilyl)oxy]methyl}oxolan-2-yl]-8-{[3-(^2H₃)methyl-8-methylimidazo[4,5-f]quinoxalin-2-yl]amino}-1H-purin-6-one
• Synonyms: N2-(Deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-d3

PROPERTIES

• Apperance: Yellow Solid
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Dimethyl Sulfoxide
• Storage Condition: Refrigerator

DETAILS

Description (English)

dG-C8-MeIQx-d3 (D239617) derivative. MeIQx-DNA adducts exist in human tissues and this adduct formation may be involved in human cancer development.

REFERENCES

• Ohshima, H., et al.: Mutat. Res., 305, 253 (1994)
• Pais, P., et al.: J. Agric. Food Chem., 47, 1098 (1994)
• Lakshmi, V., et al.: Chem. Res. Toxicol., 18, 1038 (1994)