Di-(tert-Butyl-dimethylsilyl) Curcumin

• Catalog No.: D428050
• CAS Number: 1134639-23-8
• M. F.: C33H48O6Si2
• M. W.: 596.90162

SYNONYMS

• IUPAC name: (1E,4Z,6E)-1,7-bis({4-[(tert-butyldimethylsilyl)oxy]-3-methoxyphenyl})-5-hydroxyhepta-1,4,6-trien-3-one
• IUPAC Traditional name: (1E,4Z,6E)-1,7-bis({4-[(tert-butyldimethylsilyl)oxy]-3-methoxyphenyl})-5-hydroxyhepta-1,4,6-trien-3-one
• Synonyms: (1E,4Z,6E)-1,7-Bis[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-5-hydroxy-1,4,6-heptatrien-3-one

DATABASE IDS

• CAS Number: 1134639-23-8

PROPERTIES

• Apperance: Yellow Solid
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: Ethyl Acetate
• Solubility: Methanol

DETAILS

Description (English)

Protected Curcumin (C838500). A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhi

REFERENCES

• Srinivasan, et al.: J. Pharm. Pharmacol., 5, 448 (1953)
• Tu, B., et al.: J .Cell Biol., 164, 341 (1953)
• Xu, G., et al.: Biochemistry, 44, 9817 (1953)
• Johnson, J., et al.: Cancer Lett., 255, 170 (1953)