Dibenzo[a,i]pyrene-d14

• Catalog No.: D416987
• M. F.: C24H14
• M. W.: 302.36796

SYNONYMS

• IUPAC name: (^2H₁₄)hexacyclo[10.10.2.0^2,^7.0^9,^2^3.0^1^4,^1^9.0^2^0,^2^4]tetracosa-1(22),2,4,6,8,10,12,14,16,18,20,23-dodecaene
• IUPAC Traditional name: (^2H₁₄)hexacyclo[10.10.2.0^2,^7.0^9,^2^3.0^1^4,^1^9.0^2^0,^2^4]tetracosa-1(22),2,4,6,8,10,12,14,16,18,20,23-dodecaene
• Synonyms: Benzo[rst]pentaphene-d14; Benzo[rst]pentacene-d14; Dibenzo[b,h]pyrene-d14; NSC 87521-d14; 1,2:7,8-Dibenzpyrene-d14; 3,4:9,10-Dibenzopyrene-d14

DETAILS

Description (English)

Labelled analogue of Dibenzo[a,i]pyrene, a polycyclic aromatic hydrocarbon (PAH) with potent carcinogenic activity. Dibenzo[a,i]pyrene was shown to induce DNA adduction, tumorigenicity as well as Ki-ras oncogene mutations in strain A/J mouse lung. Dibenzo

REFERENCES

• Prahalad, A.K. et al.: Carcinogenesis, 18, 1955 (1997)
• Wynder, E.L. et al.: Nature, 192, 1092 (1997)
• Homburger, F. et al.: J. Nat. Cancer Inst., 44, 357 (1997)