Dexamethasone β-D-Glucuronide

• Catalog No.: D298810
• CAS Number: 152154-28-4
• M. F.: C28H37FO11
• M. W.: 568.5851832

SYNONYMS

• IUPAC name: (2R,3R,4R,5S,6S)-6-{2-[(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl]-2-oxoethoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• IUPAC Traditional name: (2R,3R,4R,5S,6S)-6-{2-[(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl]-2-oxoethoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
• Synonyms: (11β,16α)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl β-D-Glucopyranosiduronic Acid

DATABASE IDS

• CAS Number: 152154-28-4

DETAILS

Description (English)

It is a potential prodrug for colonic delivery of the antiinflammatory corticosteroid Dexamethasone.

REFERENCES

• Fotsis, T., et al.: J. Steroid Biochem., 14, 457 (1981)
• Choi, M., et al.: Steroids, 65, 54 (1981)