(-)-Dexamethasone Acid

• Catalog No.: D298805
• CAS Number: 37927-01-8
• M. F.: C21H27FO5
• M. W.: 378.4344832
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-diene-14-carboxylic acid
• IUPAC Traditional name: (1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-diene-14-carboxylic acid
• Synonyms: 9-Fluoro-11β,17-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carboxylic Acid; (11β,16α,17α)-9-Fluoro-11,17-dihydroxy-16-methyl-3-oxo-androsta-1,4-diene-17-carboxylic Acid

DATABASE IDS

• CAS Number: 37927-01-8

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: >263°C (dec.)
• Solubility: Acetone
• Solubility: DMSO
• Solubility: Ethanol
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

A glucocorticoid receptor of spleen tumor of human, a steroid for inhibiting angiogenesis and tumor growth and treating ocular hypertension.

REFERENCES

• Manz, B., et al.: J. Steroid Biochem., 17, 335 (1982)
• Manz, B., et al.: J. Clin. Chem. Clin. Biochem., 22, 209 (1984)