Dexamethasone-d5

• Catalog No.: D298802
• CAS Number: 358731-91-6
• M. F.: C22H29FO5
• M. W.: 392.4610632
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-[2-hydroxy(^2H₂)acetyl]-2,13,15-trimethyl(6,8,8-^2H₃)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• IUPAC Traditional name: (1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-[2-hydroxy(^2H₂)acetyl]-2,13,15-trimethyl(6,8,8-^2H₃)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• Synonyms: Decaderm-d5; Decadron-d5; Dekacort-d5; Corson-d5; Decalix-d5; Decacort-d5; Decasone-d5; (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-pregna-1,4-diene-3,20-dione-d5; 16α-Methyl-9α-fluoroprednisolone-d5; Aeroseb-Dex-d5; Cortisumman-d5

DATABASE IDS

• CAS Number: 358731-91-6

PROPERTIES

• Apperance: White to Off-White Solid
• Melting Point: 230-232°C
• Solubility: Acetone
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

REFERENCES

• Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995)
• Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1995)
• Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)