Desthiazolylmethyl Ritonavir

• Catalog No.: D297450
• CAS Number: 256328-82-2
• M. F.: C33H43N5O4S
• M. W.: 605.79062
• Storage: Refrigerator

SYNONYMS

• IUPAC name: (2S)-N-[(2S)-1-[(4S,5S)-4-benzyl-2-oxo-1,3-oxazolidin-5-yl]-3-phenylpropan-2-yl]-3-methyl-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}butanamide
• IUPAC Traditional name: (2S)-N-[(2S)-1-[(4S,5S)-4-benzyl-2-oxo-1,3-oxazolidin-5-yl]-3-phenylpropan-2-yl]-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}amino)-3-methylbutanamide
• Synonyms: (2S)-3-Methyl-2-[[[methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl]amino]-N-[(1S)-1-[[(4S,5S)-2-oxo-4-(phenylmethyl)-5-oxazolidinyl]methyl]-2-phenylethyl]-butanamide

DATABASE IDS

• CAS Number: 256328-82-2

PROPERTIES

• Apperance: White Solid
• Melting Point: 65-69°C
• Solubility: Chloroform
• Solubility: DMSO
• Solubility: Methanol
• Storage Condition: Refrigerator

DETAILS

Description (English)

An analogue of the selective HIV protease inhibitor Ritonavir (R535000).

REFERENCES

• Brittain, H., et al.: Pharm. Res., 8, 963 (1991)
• Sham, H., et al.: J. Med. Chem., 39, 392 (1991)
• Phadnis, N., et al.: J. Pharm. Sci.,86, 1256 (1991)
• Bauer, J., et al.: Pharma. Res., 18, 859 (1991)