Desthiazolylmethyloxycarbonyl Ritonavir

• Catalog No.: D297430
• CAS Number: 176655-55-3
• M. F.: C32H45N5O3S
• M. W.: 579.7964
• Storage: -20°C Freezer

SYNONYMS

• IUPAC name: (2S)-N-[(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}butanamide
• IUPAC Traditional name: (2S)-N-[(2S,4S,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl]-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}amino)-3-methylbutanamide
• Synonyms: (2S)-N-[(1S,3S,4S)-4-Amino-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-3-methyl-2-[[[methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl]amino]butanamide

DATABASE IDS

• CAS Number: 176655-55-3

PROPERTIES

• Solubility: Tetrahydrofuran
• Apperance: Off-White Solid
• Melting Point: 73-74°C
• Solubility: Acetone
• Solubility: Chloroform
• Solubility: Dichloromethane
• Solubility: DMSO
• Storage Condition: -20°C Freezer

DETAILS

Description (English)

A labelled metabolite of the selective HIV protease inhibitor Ritonavir (R535000).

REFERENCES

• Jaworski, T., et al.: Xenobiotica, 21, 1451 (1991)
• Lee, S., et al.: Biochem. Pharmacol., 49, 1567 (1991)
• Zhang, X., et al.: Drug Metab. Dispos., 24, 23 (1991)