N-Desmethyl Tadalafil

• Catalog No.: D293800
• CAS Number: 171596-36-4
• M. F.: C21H17N3O4
• M. W.: 375.37738

SYNONYMS

• IUPAC name: (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-3,6,17-triazatetracyclo[8.7.0.0^3,^8.0^1^1,^1^6]heptadeca-1(10),11,13,15-tetraene-4,7-dione
• IUPAC Traditional name: (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-3,6,17-triazatetracyclo[8.7.0.0^3,^8.0^1^1,^1^6]heptadeca-1(10),11,13,15-tetraene-4,7-dione
• Synonyms: (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione; Nortadalafil; (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione

DATABASE IDS

• CAS Number: 171596-36-4

DETAILS

Description (English)

A N-desmethyl analogue of the human PDE5 inhibitor Tadalafil (T004500). A potential antiplasmodial drug.

REFERENCES

• Beghyn, T. et al.: Bioorg. Med. Chem. Lett., 17, 789 (2007)
• Daugan, A. et al.: J. Med. Chem., 46, 4533 (2007)